Russia’s and China’s scientists have developed a new method of increasing the strength of a biodegradable polymer used for creating artificial bones and cartilage. According to the Russian Science Foundation (RSF), the proposed approach can be easily scaled for industrial production.
The study authors note that biodegradable polymers, unlike traditional plastics, ‘are capable of breaking down into harmless components in the environment, reducing the risk of soil and water pollution.’
Polycaprolactone, one such polymer, is known for its strength and biocompatibility, making it an ideal material for implants.
‘Polycaprolactone is obtained through polymerization, where small molecules become links in one long chain. This process occurs in the presence of catalysts—substances that accelerate the chemical reaction,’ states the RSF announcement.
However, traditional tin-based catalysts are toxic and require high temperatures. The scientists proposed using Krossing’s acid, which contains aluminum.
The study authors note that biodegradable polymers, unlike traditional plastics, ‘are capable of breaking down into harmless components in the environment, reducing the risk of soil and water pollution.’
Polycaprolactone, one such polymer, is known for its strength and biocompatibility, making it an ideal material for implants.
‘Polycaprolactone is obtained through polymerization, where small molecules become links in one long chain. This process occurs in the presence of catalysts—substances that accelerate the chemical reaction,’ states the RSF announcement.
However, traditional tin-based catalysts are toxic and require high temperatures. The scientists proposed using Krossing’s acid, which contains aluminum.
‘We have discovered an effective catalyst—Krossing’s acid—for synthesizing polycaprolactone. The catalyst’s high activity not only enables controlled polymer synthesis under mild conditions but also allows the reaction to proceed with very small amounts of catalyst. This makes it significantly superior to the classic, more toxic tin-based system,’ said Andrey Kozlov, a researcher at the A. N. Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences.
This new method allows synthesizing polycaprolactone with approximately 950 links, improving its mechanical properties and durability. The scientists were also able to identify optimal polymerization conditions.
Moving forward, the researchers plan to adapt this method for wide industrial applications.
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Moving forward, the researchers plan to adapt this method for wide industrial applications.
Source